Substance Use Disorders (SUD) are chronic relapsing medical conditions characterized by compulsive substance seeking and use. They constitute a substantial disease burden globally. Labeling of persons with SUD has created barriers to treatment but there are effective management strategies. The dental profession has embraced reforms designed to address the SUD epidemic by promoting continuing education for practitioners and initiating curriculum changes in dental schools. Screening, Brief Intervention and Referral to Treatment (SBIRT) is an evidence-based model for managing patients with SUD.
The use of a formative 1-station Objective Structured Clinical Examination (OSCE) for learning and assessment in SBIRT, operationalized with the MD3 rating scale is presented in this study. In 3 years of implementation, the SBIRT OSCE successfully integrated into the curriculum of the College of Dental Medicine, Columbia University. Mean score of total adherent behaviours was 11.80 (SD = 4.23) (range: 2 – 24) and Cronbach’s coefficient alpha for across-items reliability in adherent behaviours was 0.66. Adherent behaviours correlated with the global ratings (r = 0.66). Mean of global rating scores were 2.90 (SD = 1.01) for collaboration and 2.97 (SD = 1.00) for empathy and the global rating scores correlated with each other (r = 0.85). Histograms of global rating scores resembled normal distribution. The 1-station OSCE is a good model for learning about SBIRT. Psychometric analysis was useful in understanding the underlying construct of the MD3 rating scale and supported its reliability, validity and utility in dental education.
Delivering online alternatives to the anatomy laboratory: early experience during the COVID-19 pandemic
Social distancing measures due to the COVID-19 pandemic will make anatomy dissecting room practicals difficult, if not impossible to run at some institutions in the upcoming academic year. The learning community that exists within physical anatomy practicals needs to be moved online. Virtual replacement of visuo-spatial and social elements of learning anatomy pose particular challenges to educators.
Our department has trialled Blackboard Collaborate, an online communication platform in conjunction with Visible Body, a 3D anatomical modelling program. We have delivered 266 hours of synchronous small group teaching to medical and physician associate students. We describe this approach and discuss the relevance of distance learning pedagogy to the design of new online anatomy teaching and development of online learning communities. This article is protected by copyright. All rights reserved.
Attitudes of key professionals towards people with intellectual disabilities and their inclusion in society: A qualitative study in an Indonesian context
This study aimed to explore key professionals’ attitudes towards people with intellectual disability (ID) and inclusion of said people in the community. Eighteen participants from three professional groups, comprising health practitioners (medical doctors, psychologists), mainstream/special education teachers, and religious leaders (Islam, Catholicism, Protestantism, Hinduism, and Buddhism) were recruited. Semistructured interviews, aided by two vignettes depicting mild and severe ID, were conducted.
Thematic analysis was used to analyse the data. Seven themes were identified exploring: perceived causes; use of terminology; attitudes towards people with ID; attitudes towards inclusion, religion and ID; family-centric support; and challenges faced by people with ID in a wider context. Perceived capabilities of persons with ID were found to influence attitudes towards people with ID and their inclusion. Availability and accessibility of good quality services were also found to influence attitudes towards the inclusion of people with ID. Cultural factors related to attitudes towards ID are discussed.
The Great Gamble? A Mixed-Methods Study of Factors In˜fluencing Medical Students in Specialty Choice
Career planning remains relatively unexplored as a domain of medical education. Our aim was to explore the career planning journey undertaken by medical students. Results Approximately one third of participants had decided their future specialty. Important factors in career choice were ‘interest in specific [specialty] aspects,’ ‘work-life balance,’ ‘personality type’ of others in the specialty, an enjoyable experience on rotation and role models. Negative influential factors included poor conduct of doctors encountered and negative portrayals of specialities by practicing doctors. Conclusion The undergraduate and early postgraduate periods are formative times in career planning for junior doctors. Students and interns/FY1s are strongly influenced by doctors in the clinical setting, and clinicians should be aware of this power to exert both positive and negative influence.

Dawning of Onco-Cardiology
Recent progress in cancer therapy has decreased all-cancer mortality, but cardiovascular adverse events owing to chemotherapy and radiotherapy have greater impact on clinical outcome and quality of life in cancer patients and survivors. There are a wide variety of cardiovascular adverse events related to cancer therapy, and the opportunities requiring specialized care by cardiovascular experts are increasing in clinical practice. Under such circumstances, onco-cardiology is becoming very important as a new discipline and attracting much attention in Japan.
Rat IgG (Fc) fragment, purified (isotype control) |
20005-1-FC |
Alpha Diagnostics |
0.5 mg |
EUR 250 |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] |
VAng-1451Lsx-100g |
Creative Biolabs |
100 µg |
EUR 848 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] |
VAng-1451Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 4724 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] [Avi] |
VAng-1452Lsx-200g |
Creative Biolabs |
200 µg |
EUR 3844 |
Description: Biotinylated Human Dkk-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: O94907-1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Fc] [Avi] |
VAng-1452Lsx-25g |
Creative Biolabs |
25 µg |
EUR 1013 |
Description: Biotinylated Human Dkk-1, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: O94907-1) |
Rat IgG (Fc)-Biotin Conjuagte (isotype control), purified |
20005-1-FC-B |
Alpha Diagnostics |
0.1 mg |
EUR 225 |
Rat IgG (Fc)-FITC Conjuagte (isotype control), purified |
20005-1-FC-F |
Alpha Diagnostics |
0.1 mg |
EUR 225 |
Rat IgG (Fc)-HRP Conjuagte (isotype control), purified |
20005-1-FC-HP |
Alpha Diagnostics |
0.1 mg |
EUR 225 |
Human IgG (Fc) fragment, purified (>95%, low endotoxin) |
20007-1-FC-LE |
Alpha Diagnostics |
100 ul |
EUR 225 |
Sheep IgG-Fc ELISA Kit, 96 tests, Quantitative |
7615-Fc |
Alpha Diagnostics |
1 kit |
EUR 712 |
Horse IgG-Fc ELISA Kit, 96 tests, Quantitative |
7715-Fc |
Alpha Diagnostics |
1 kit |
EUR 712 |
Dog IgG (Fc) fragment (isotype control, non-immune), purified |
20016-FC |
Alpha Diagnostics |
0.5 mg |
EUR 250 |
Dkk-1 Polyclonal Antibody |
41928-100ul |
SAB |
100ul |
EUR 252 |
Dkk-1 Polyclonal Antibody |
41928-50ul |
SAB |
50ul |
EUR 187 |
Dkk-1 Polyclonal Antibody |
ABP53293-003ml |
Abbkine |
0.03ml |
EUR 158 |
- Immunogen information: Synthesized peptide derived from the C-terminal region of human Dkk-1
- Applications tips:
|
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
Dkk-1 Polyclonal Antibody |
ABP53293-01ml |
Abbkine |
0.1ml |
EUR 289 |
- Immunogen information: Synthesized peptide derived from the C-terminal region of human Dkk-1
- Applications tips:
|
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
Dkk-1 Polyclonal Antibody |
ABP53293-02ml |
Abbkine |
0.2ml |
EUR 414 |
- Immunogen information: Synthesized peptide derived from the C-terminal region of human Dkk-1
- Applications tips:
|
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1 |
Dkk-1 Polyclonal Antibody |
ES4292-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Dkk-1 Polyclonal Antibody |
ES4292-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
Anti-Dkk-1 antibody |
STJ97257 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: Rabbit polyclonal to Dkk-1. |
Anti-Dkk-1 antibody |
STJ98000 |
St John's Laboratory |
100 µl |
EUR 234 |
Description: Mouse monoclonal to Dkk-1. |
Human IgG Fc-Biotin conjugate (isotype control, non-immune), purified |
20007-1-Fc-B |
Alpha Diagnostics |
0.1 mg |
EUR 164 |
Human IgG Fc-FITC conjugate (isotype control, non-immune), purified |
20007-1-Fc-F |
Alpha Diagnostics |
0.1 mg |
EUR 164 |
Human IgG Fc-HRP conjugate (isotype control, non-immune), purified |
20007-1-Fc-HP |
Alpha Diagnostics |
0.1 mg |
EUR 164 |
IGF-1-Fc |
E13-m003-1 |
EnoGene |
10μg |
EUR 291 |
Recombinant (HEK) Rabbit IgG (Fc) (101-323aa, 185Thr/Asn284Ser, ~33 kda, >95%, Low Endotoxin) |
20009-1-R-FC |
Alpha Diagnostics |
50 ug |
EUR 286 |
Dkk-1 Polyclonal Conjugated Antibody |
C41928 |
SAB |
100ul |
EUR 397 |
Human DKK-1 ELISA kit |
LF-EK50797 |
Abfrontier |
1×96T |
EUR 648 |
Recombinant Human DKK-1 Protein |
PROTO94907-3 |
BosterBio |
10ug |
EUR 317 |
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues. |
Recombinant Mouse Dkk-1 Protein |
RP01062 |
Abclonal |
5 μg |
EUR 183 |
Human IgG (Fc) fragment-Biotin purified (>95%, low endotoxin) |
20007-1-FC-LE-B |
Alpha Diagnostics |
25 ug |
EUR 286 |
Goat IgG (fc)-Biotin conjugate (isotype control) |
20011-Fc-B |
Alpha Diagnostics |
100 ug |
EUR 164 |
Goat IgG (fc)-FITC conjugate (isotype control) |
20011-Fc-F |
Alpha Diagnostics |
100 ug |
EUR 164 |
Goat IgG (fc)-HRP conjugate (isotype control) |
20011-Fc-HP |
Alpha Diagnostics |
100 ug |
EUR 164 |
FC 131 |
B7647-1 |
ApexBio |
1 mg |
EUR 187 |
Dkk-3 antibody |
22898-100ul |
SAB |
100ul |
EUR 390 |
Dog IgG (Fc) fragment (isotype control, non-immune), purified |
20016-3-FC |
Alpha Diagnostics |
0.5 mg |
EUR 250 |
Human CellExp? DKK-1, Human Recombinant |
7132-10 |
Biovision |
|
EUR 278 |
Human CellExp? DKK-1, Human Recombinant |
7132-50 |
Biovision |
|
EUR 1132 |
ELISA kit for Human DKK-1 |
EK5390 |
SAB |
96 tests |
EUR 553 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
ELISA kit for Rat DKK-1 |
EK5668 |
SAB |
96 tests |
EUR 553 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Rat DKK-1 in samples from serum, plasma, tissue homogenates and other biological fluids. |
Human DKK-1 PicoKine ELISA Kit |
EK0867 |
BosterBio |
96 wells |
EUR 425 |
Description: For quantitative detection of human DKK1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
OPG-Fc Osteoprotegerin Human Recombinant Protein /Fc Chimera |
PROTO00300-1 |
BosterBio |
Regular: 50ug |
EUR 317 |
Description: Recombinant OPG produced in yeast contains 2x412 amino acid residues, including 180 residues from mature OPG (a.a 22-201) and 232 residues from the Fc protein of human IgG1, and has a calculated molecular mass of 109.6kDa.  |
Dog IgG Fc-Biotin Conjugate (isotype control, non-immune), purified |
20016-FC-B |
Alpha Diagnostics |
0.1 mg |
EUR 225 |
Dog IgG Fc-FITC Conjugate (isotype control, non-immune), purified |
20016-FC-F |
Alpha Diagnostics |
0.1 mg |
EUR 225 |
Dog IgG Fc-HRP Conjugate (isotype control, non-immune), purified |
20016-FC-HP |
Alpha Diagnostics |
0.1 mg |
EUR 225 |
SCF-Fc |
E13-m004-1 |
EnoGene |
10μg |
EUR 343 |
Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His) |
CC49-10ug |
Novoprotein |
10ug |
EUR 156 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2. |
Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His) |
CC49-1mg |
Novoprotein |
1mg |
EUR 2283 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2. |
Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His) |
CC49-500ug |
Novoprotein |
500ug |
EUR 1613 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2. |
Recombinant Human Dickkopf-Related Protein 2/DKK-2 (N-Fc, C-6His) |
CC49-50ug |
Novoprotein |
50ug |
EUR 369 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.2. |
Dkk-3 Polyclonal Antibody |
ABP54542-003ml |
Abbkine |
0.03ml |
EUR 158 |
- Immunogen information: Synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160
- Applications tips:
|
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160 |
Dkk-3 Polyclonal Antibody |
ABP54542-01ml |
Abbkine |
0.1ml |
EUR 289 |
- Immunogen information: Synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160
- Applications tips:
|
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160 |
Dkk-3 Polyclonal Antibody |
ABP54542-02ml |
Abbkine |
0.2ml |
EUR 414 |
- Immunogen information: Synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160
- Applications tips:
|
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160 |
Dkk-3 Polyclonal Antibody |
ES5541-100ul |
ELK Biotech |
100ul |
EUR 279 |
Description: A Rabbit Polyclonal antibody against Dkk-3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
Dkk-3 Polyclonal Antibody |
ES5541-50ul |
ELK Biotech |
50ul |
EUR 207 |
Description: A Rabbit Polyclonal antibody against Dkk-3 from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA |
Anti-Dkk-3 antibody |
STJ92720 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: Rabbit polyclonal to Dkk-3. |
Anti-Dkk-3 antibody |
STJ98001 |
St John's Laboratory |
100 µl |
EUR 234 |
Description: Mouse monoclonal to Dkk-3. |
Recombinant (HEK) Human IgG3-Fc (99-377aa, His-tag, >95%, low endotoxin) |
20007-G3-FC |
Alpha Diagnostics |
50 ug |
EUR 286 |
Human DKK-1 ELISA kit (4×96T) |
LF-EK50798 |
Abfrontier |
4×96T |
EUR 2201 |
SDF-1α-Fc |
E13-m001-1 |
EnoGene |
10μg |
EUR 291 |
VEGF-121-Fc |
E13-m005-1 |
EnoGene |
10μg |
EUR 343 |
VEGF-165-Fc |
E13-m006-1 |
EnoGene |
10μg |
EUR 343 |
IL-2-Fc |
E13-m007-1 |
EnoGene |
10μg |
EUR 310 |
Recombinant (HEK) Human IgG1 Fc (103Cys/Ser, 99-330aa, His-tag, >95%, low endotoxin) |
20007-G1-FC |
Alpha Diagnostics |
50 ug |
EUR 286 |
Recombinant (HEK) Human IgG2-Fc (257Ser/Ala, 99-327aa, His-tag, >95%, low endotoxin) |
20007-G2-FC |
Alpha Diagnostics |
50 ug |
EUR 286 |
Recombinant (HEK) Human IgG4-Fc (108Ser/Pro, 99-327aa, His-tag, >95%, low endotoxin) |
20007-G4-FC |
Alpha Diagnostics |
50 ug |
EUR 286 |
Recombinant (HEK) Mouse IgG2a-Fc (98-330aa, ~34 kda, His-tag, >95%, low endotoxin) |
20102-102-FC |
Alpha Diagnostics |
50 ug |
EUR 286 |
Recombinant (HEK) Mouse IgG2b-Fc (97-335aa, ~37 kda, His-tag, >95%, low endotoxin) |
20102-103-FC |
Alpha Diagnostics |
50 ug |
EUR 286 |
Recombinant (HEK) Mouse IgG3-Fc (97-329aa, ~33 kda, His-tag, >95%, low endotoxin) |
20102-104-FC |
Alpha Diagnostics |
50 ug |
EUR 286 |
Recombinant Human CD47 Protein, His-Fc (IgG), Insect-10ug |
QP11336-HIS-Fc-10ug |
EnQuireBio |
10ug |
EUR 201 |
PinPoint-FC attP Placement Vector |
PIN300A-1 |
SBI |
10ug |
EUR 778 |
- Category: PinPoint Integrase Tools
|
Human DKK-1(Dickkopf-related protein 1) ELISA Kit |
EH0113 |
FN Test |
96T |
EUR 524.1 |
- Detection range: 31.25-2000 pg/ml
- Uniprot ID: O94907
- Alias: DKK1/dickkopf(Xenopus laevis) homolog 1/dickkopf homolog 1(Xenopus laevis)/dickkopf related protein-1/Dickkopf-1/dickkopf-related protein 1/Dkk-1/DKK-1/SKdickkopf-1 like
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
Recombinant Human Dkk-3 Protein |
RP00355 |
Abclonal |
10 μg |
EUR 164 |
Recombinant (HEK) Mouse IgG1-Fc (98-321aa, 102Cys/Ser, ~32 kda, His-tag, >95%, low endotoxin) |
20102-101-FC |
Alpha Diagnostics |
50 |
EUR 286 |
FLT4-Fc Vascular Endothelial Growth Factor Receptor-3 Fc Chimera Human Recombinant Protein |
PROTP35916-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Soluble FLT4 Human Recombinant fused with the Fc part of human IgG1 produced in baculovirus is a monomeric, glycosylated, polypeptide containing 774 amino acids and having a molecular mass of 260 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding.;The FLT4 Fc Chimera is purified by proprietary chromatographic techniques. |
Dkk-1 ELISA Kit (Human) : 96 Wells (OKAG00221) |
OKAG00221 |
Aviva Systems Biology |
96 Wells |
EUR 596 |
Description: Description of target: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 63 pg/mL |
TNFRSF14 HVEM-Fc Human Recombinant Protein |
PROTO43557-1 |
BosterBio |
Regular: 100ug |
EUR 317 |
Description: TNFRSF14 Human Recombinant produced in Pichia Pastoris is a single, glycosylated, polypeptide chain containing 396 amino acids and having a molecular mass of 58.0kDa.  |
Recombinant Human FGFR1a (IIIc) Fc Protein |
PROTP11362-1 |
BosterBio |
50ug |
EUR 317 |
Description: The FGF family plays a central role during prenatal development and postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. The FGF ligands bind to a family of type I transmembrane tyrosine kinase receptors which leads to dimerization and activation by sequential autophosphorylation of specific tyrosine residues. Four genes encoding structurally related FGF receptors (FGFR-1 to -4) are known. Alternative splicing of the mRNAs generates numerous multiple forms of FGFR-1 to -3. Alternate forms of FGF receptors can exhibit different specificities with respect to ligand binding. For example, the form designated as FGFR1a (IIc) interacts predominantly with FGF-acidic (FGF1) and FGF-basic (FGF2). A frequent splicing event involving FGFR-1 and -2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform. Only the alpha isoform has been identified for FGFR-3 and FGFR-4. Additional splicing events for FGFR-1 to -3, involving the C-terminal half of the IgIII domain encoded by two mutually exclusive alternative exons, generate FGF receptors with alternative IgIII domains (IIIb and IIIc). Recombinant human FGFR1a (IIIc) is a 65.2 kDa protein containing 586 amino acids. Under reducing conditions, FGFR1a migrates between 100-110 kDa on SDS-PAGE gel. |
Human EPOR / Erythropoietin Receptor Protein (Fc Tag) |
G1011-.1 |
ApexBio |
100 µg |
EUR 696 |
Recombinant Dkk-1 Protein (Thr 32-His 266) [His] |
VAng-1453Lsx-100g |
Creative Biolabs |
100 µg |
EUR 1013 |
Description: Human Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [His] |
VAng-1453Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 4999 |
Description: Human Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep] |
VAng-1454Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 6374 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep] |
VAng-1454Lsx-250g |
Creative Biolabs |
250 µg |
EUR 2470 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 266) [Strep] |
VAng-1454Lsx-25g |
Creative Biolabs |
25 µg |
EUR 765 |
Description: Human Dkk-1, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: NP_036374.1) |
Recombinant Dkk-1 Protein (Thr 32-His 272) [His] |
VAng-1455Lsx-500g |
Creative Biolabs |
500 µg |
EUR 4449 |
Description: Mouse Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: O54908) |
Recombinant Dkk-1 Protein (Thr 32-His 272) [His] |
VAng-1455Lsx-50g |
Creative Biolabs |
50 µg |
EUR 1013 |
Description: Mouse Dkk-1, His tag, is expressed in HEK 293 cells. (Uniprot ID: O54908) |
Human DKK-4 PicoKine ELISA Kit |
EK0868 |
BosterBio |
96 wells |
EUR 455 |
Description: For Quantitative Detection of human DKK-4 in cell culture supernates, serum and plasma(heparin, EDTA). |
Human DKK-3 PicoKine ELISA Kit |
EK1323 |
BosterBio |
96 wells |
EUR 425 |
Description: For quantitative detection of human DKK-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA). |
Recombinant Human Dkk-3/DKK3 Protein |
RP00209 |
Abclonal |
10 μg |
EUR 155 |
DKK-3 ELISA Kit (Human) (OKBB00603) |
OKBB00603 |
Aviva Systems Biology |
96 Wells |
EUR 505 |
Description: Description of target: Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. It is mapped to 11p15.3. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Members of the Dkk-related family display unique patterns of mRNA expression in human and mouse tissues, and are secreted when expressed in 293T cells. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL |
IGF-1-Fc |
E13-m003-2 |
EnoGene |
50μg |
EUR 830 |
TEK Tyrosine Kinase Endothelial Fc Chimera Mouse Recombinant Protein |
PROTQ02858-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Soluble TEK Mouse Recombinant fused with the Fc part of human IgG1 produced in CHO is a glycosylated disulfide-linked homodimer, polypeptide containing amino acids 119-740 amino acids and having a total molecular mass of 280 kDa. Mouse TIE-2/Fc monomer has a calculated molecular mass of approximately 105 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 140 kDa protein in SDS-PAGE under reducing conditions.;The TEK Fc Chimera is purified by proprietary chromatographic techniques. |
FGFR2 Fibroblast Growth Factor Receptor 2 Fc ChimeraHuman Recombinant Protein |
PROTP21802-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Soluble FGFR-2a (IIIc) Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric, glycosylated, Polypeptide chain and having a molecular mass of 195 kDa. ;The FGFR2 is purified by proprietary chromatographic techniques. |
Contactin-1, FC Chimera |
PR15072 |
Neuromics |
100 ug |
EUR 474 |
TIE-1 Fc Chimera |
PR27153 |
Neuromics |
2 ug |
EUR 191 |
FGFR4 Fibroblast Growth Factor Receptor 4 Fc Chimera Human Recombinant Protein |
PROTP22455-1 |
BosterBio |
Regular: 10ug |
EUR 317 |
Description: Soluble FGFR-4a (IIIc) Fc Chimera Human Recombinant fused with Xa cleavage site with the Fc part of human IgG1 produced in baculovirus is a heterodimeric, glycosylated, Polypeptide chain and having a molecular mass of 170 kDa. ;The FGFR4 is purified by proprietary chromatographic techniques. |
Plastic Columns Frits |
FC-100 |
ABTBeads |
100/pk |
EUR 122 |
Plastic Columns Frits |
FC-50 |
ABTBeads |
50/pk |
EUR 83 |
PD-1/PDCD1(Fc fusion) |
E21-J97 |
EnoGene |
10ug |
EUR 343 |
Human DKK-3(Dickkopf-related protein 3) ELISA Kit |
EH0114 |
FN Test |
96T |
EUR 567.6 |
- Detection range: 62.5-4000 pg/ml
- Uniprot ID: Q9UBP4
- Alias: DKK-3/Dickkopf-3/Dkk3/REIC
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml |
Recombinant Dkk-3 Protein (Pro 23-Ile 349) [His] |
VAng-1456Lsx-1mg |
Creative Biolabs |
1 mg |
EUR 5494 |
Description: Mouse Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_056629.1) |
Recombinant Dkk-3 Protein (Pro 23-Ile 349) [His] |
VAng-1456Lsx-50g |
Creative Biolabs |
50 µg |
EUR 848 |
Description: Mouse Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_056629.1) |
Recombinant Dkk-3 Protein (Pro 23-Ile 350) [His] |
VAng-1457Lsx-200g |
Creative Biolabs |
200 µg |
EUR 1123 |
Description: Human Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001018067.1) |
Recombinant Dkk-3 Protein (Pro 23-Ile 350) [His] |
VAng-1457Lsx-20g |
Creative Biolabs |
20 µg |
EUR 380 |
Description: Human Dkk-3, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001018067.1) |
PinPoint-FC 293T Platform Cell Line for Targeted Gene Insertion (with PinPoint site already placed) |
PIN320A-1 |
SBI |
>2x10^5 cells |
EUR 3104 |
- Category: PinPoint Integrase Tools
|
The Japanese Onco-Cardiology Society was established in 2017, and continues integration of academic activities to solve challenging problems in this field. Interdisciplinary collaborations between cardiologists and oncologists will be further progressed in medical care, clinical and basic research, and education.